30 Apr 2020

Clinical characteristics of coronavirus disease 2019 in China

The clinical characteristics of 1,099 patients with COVID-19 in China was recently published in the highly esteemed New England Journal of Medicine. Professor Kwok-Yung Yuen collaborated with several experts to analyse the symptoms and laboratory findings of these patients.

Key takeaways from the study:

  1. The median age was 47 years
  2. Very few were children, with <0.9% of patients aged 15 years or younger
  3. In this group of patients, the median duration for symptoms to appear after infection was 4 days
  4. The two most common symptoms were fever (88.7%) and cough (67.8%)
  5. Nausea, vomiting and diarrhoea were uncommon
  6. 91.1% of patients were diagnosed with pneumonia
  7. Patients were hospitalised for a median duration of 12 days
  8. 5% of patients were admitted to an intensive care unit
  9. 2.3% of patients required mechanical ventilation to help with breathing
  10. 1.4% of patients died

This study’s finding was that SARS-CoV-2, the 2019 coronavirus, appears to cause fewer deaths than the viruses that caused SARS or MERS outbreak; however, patients with long-term respiratory diseases do have worse outcomes.

To read the original article published in The New England Journal of Medicine, click here.